Gene editing, also known as genome editing, is a group of technologies that allow genetic material to be removed, inserted, replaced or modified at precise locations in a genome to correct genetic defects or correct DNA sequences. Gene editing technology is gaining major traction in disease diagnostics and treatments. It holds immense potential to treat previously incurable human diseases like sickle cell disease, beta-thalassemia, cystic fibrosis and several type of cancers.
The Global Gene Editing Market is estimated to be valued at US$ 11.2 Billion in 2024 and is expected to exhibit a CAGR of 10% over the forecast period 2025-2030.
Key Takeaways
Key players operating in the gene editing market are CRISPR Therapeutics, Editas Medicine, Intellia Therapeutics, Cellectis and Sangamo Therapeutics. CRISPR Therapeutics and its partner Vertex Pharmaceuticals are developing several gene therapies for blood disorders and NASH using CRISPR-Cas9 technology.
The growing prevalence of Gene Editing Market Demand disorders and cancer worldwide are majorly driving the demand for gene editing technologies. Gene editing finds wide applications in treatment of hereditary diseases, drug discovery and development and agricultural biotechnology. It is also seen as a promising solution for developing resilient crops.
Technological advancements have enabled precise and effective gene editing. The development of CRISPR-Cas9 technology has revolutionized genome editing capabilities. It allows targeting and editing of DNA with greater flexibility and precision compared to previous technologies like zinc finger nucleases and transcription activator-like effector nucleases. This has expanded the scope and applications of gene editing.
Market Trends
In-vivo gene editing applications - Researchers are developing new approaches to directly deliver gene editing machinery to target cells inside the body for in-vivo therapeutic effect. This avoids complex cell extraction and re-administration procedures.
Combinatorial gene editing - Combining CRISPR with other technologies like base editing, prime editing and homology-directed repair promises to expand the capabilities of genome editing for complex disease applications.
Market Opportunities
Agricultural applications - Gene editing holds promise to develop climate-resilient and higher yielding crop varieties. This presents major opportunities in the agricultural biotech market.
Cell and gene therapy applications - Effective gene therapies for curing genetic disorders like sickle cell disease, cystic fibrosis, blood cancers etc. using technologies like CRISPR-Cas9 system can capture a large market share.
Impact of COVID-19 on Gene Editing Market Growth
The COVID-19 pandemic has significantly impacted the gene editing market globally. During the initial outbreak, most research activities and clinical trials came to a halt due to lockdowns and social distancing measures. This led to delays in product development timelines and negatively impacted the market growth in 2020. However, with resurgence of virus mutations and variants, gene editing has gained prominence for developing more effective diagnostics, vaccines and therapeutics.
Many companies are collaborating to advance the development of CRISPR based therapies and tools to fight COVID-19. Researchers are also exploring gene editing's potential to generate resistant cell lines and animal models. Numerous clinical trials evaluating CRISPR's ability to edit immune cells like T-cells and generate resistance in participants are now underway. As the pandemic continues to evolve, focus on developing gene and cell therapies is expected to accelerate.
With lockdowns easing in many regions, research activities have resumed though challenges around ensuring safety of lab staff and maintaining supply chains persist. The crisis has underscored the need for innovation in healthcare sector. Governments and investors are pouring more funds to accelerate development of novel genetic solutions. While short term growth was impacted, the pandemic has enhanced long term opportunities for gene editing market as it aims to prevent future outbreaks and bolster public health preparedness worldwide.
Concentration of Gene Editing Market by Geographical Regions
North America region currently dominates the global gene editing market and holds more than 35% of total market share in terms of value. This is attributed to presence of leading biotech and pharmaceutical companies, availability of funding for research projects and streamlined regulatory landscape supportive of genetic research applications.
Asia pacific region is identified as the fastest growing market for gene editing globally. China, South Korea and Japan are driving significant growth in the region. Factors such as government initiatives, liberal funding schemes, presence of contract research organizations and rising awareness are fueling adoption. Major pharmaceutical players are also focusing on expanding their operations in Asia to tap into the growth opportunities.
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Money Singh is a seasoned content writer with over four years of experience in the market research sector. Her expertise spans various industries, including food and beverages, biotechnology, chemical and materials, defense and aerospace, consumer goods, etc. (https://www.linkedin.com/in/money-singh-590844163)